Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Homo sapiens (Human)) | BDBM50529848
(CHEMBL4452926)Show SMILES CCCCCCOc1ccc(Cl)cc1COc1ccccc1C(=O)Nc1cccnc1 Show InChI InChI=1S/C25H27ClN2O3/c1-2-3-4-7-15-30-23-13-12-20(26)16-19(23)18-31-24-11-6-5-10-22(24)25(29)28-21-9-8-14-27-17-21/h5-6,8-14,16-17H,2-4,7,15,18H2,1H3,(H,28,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description
Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol... |
Eur J Med Chem 163: 864-882 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.028
BindingDB Entry DOI: 10.7270/Q2NZ8C4J |
More data for this
Ligand-Target Pair | |
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Homo sapiens (Human)) | BDBM50529848
(CHEMBL4452926)Show SMILES CCCCCCOc1ccc(Cl)cc1COc1ccccc1C(=O)Nc1cccnc1 Show InChI InChI=1S/C25H27ClN2O3/c1-2-3-4-7-15-30-23-13-12-20(26)16-19(23)18-31-24-11-6-5-10-22(24)25(29)28-21-9-8-14-27-17-21/h5-6,8-14,16-17H,2-4,7,15,18H2,1H3,(H,28,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description
Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol... |
Eur J Med Chem 163: 864-882 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.028
BindingDB Entry DOI: 10.7270/Q2NZ8C4J |
More data for this
Ligand-Target Pair | |