Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 482.6 BDBM50227659

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Rattus norvegicus)	BDBM50227659 (2-(2-(3-(4-isopropylphenyl)-1-pentylureido)-2,3-di...) Show SMILES CCCCCN(C1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)Nc1ccc(cc1)C(C)C |w:6.5| Show InChI InChI=1S/C28H38N2O3S/c1-6-7-8-15-30(27(33)29-23-12-9-20(10-13-23)19(2)3)24-16-21-11-14-25(18-22(21)17-24)34-28(4,5)26(31)32/h9-14,18-19,24H,6-8,15-17H2,1-5H3,(H,29,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	159	n/a	n/a	n/a	n/a
Johnson& Johnson Curated by ChEMBL					Assay Description Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene induction				Bioorg Med Chem Lett 17: 6773-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.041 BindingDB Entry DOI: 10.7270/Q27945H6
					More data for this Ligand-Target Pair