Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 498.4 BDBM176297

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM176297 (US9688696, 12) Show SMILES CCCCCc1nccc(n1)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C26H29Cl2N5O/c1-2-3-4-8-24-29-14-13-23(30-24)19-9-11-20(12-10-19)32-15-17-33(18-16-32)26(34)31-25-21(27)6-5-7-22(25)28/h5-7,9-14H,2-4,8,15-18H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
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