Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 459.5 BDBM50540561

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540561 (CHEMBL4643748) Show SMILES CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O3/c1-4-5-20-29-27(32)28(2,3)34-26-15-11-22(12-16-26)19-21-33-25-17-13-24(14-18-25)31-30-23-9-7-6-8-10-23/h6-18H,4-5,19-21H2,1-3H3,(H,29,32)/b31-30+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
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