Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin D
(Homo sapiens (Human)) | BDBM50071559
((S)-2-[2-(Naphthalen-2-yloxy)-acetylamino]-pentane...)Show SMILES CCCCNC(=O)CC(O)C(Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)COc1ccc2ccccc2c1 Show InChI InChI=1S/C32H40N4O6/c1-2-3-17-34-30(39)20-28(37)27(18-22-9-5-4-6-10-22)36-32(41)26(15-16-29(33)38)35-31(40)21-42-25-14-13-23-11-7-8-12-24(23)19-25/h4-14,19,26-28,37H,2-3,15-18,20-21H2,1H3,(H2,33,38)(H,34,39)(H,35,40)(H,36,41)/t26-,27?,28?/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against cathepsin D |
Bioorg Med Chem Lett 8: 2315-20 (1999)
BindingDB Entry DOI: 10.7270/Q2SN09G9 |
More data for this
Ligand-Target Pair | |
Plasmepsin II
(Plasmodium falciparum) | BDBM50071559
((S)-2-[2-(Naphthalen-2-yloxy)-acetylamino]-pentane...)Show SMILES CCCCNC(=O)CC(O)C(Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)COc1ccc2ccccc2c1 Show InChI InChI=1S/C32H40N4O6/c1-2-3-17-34-30(39)20-28(37)27(18-22-9-5-4-6-10-22)36-32(41)26(15-16-29(33)38)35-31(40)21-42-25-14-13-23-11-7-8-12-24(23)19-25/h4-14,19,26-28,37H,2-3,15-18,20-21H2,1H3,(H2,33,38)(H,34,39)(H,35,40)(H,36,41)/t26-,27?,28?/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc.
Curated by ChEMBL
| Assay Description
In vitro inhibition of plasmepsin-2 from Plasmodium falciparum. |
Bioorg Med Chem Lett 8: 2315-20 (1999)
BindingDB Entry DOI: 10.7270/Q2SN09G9 |
More data for this
Ligand-Target Pair | |