Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 424.4 BDBM50574980

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50574980 (CHEMBL4878808) Show SMILES CCCCOc1ccc2C(=O)\C(Oc2c1)=C\c1cc(C)c(OC(C)(C)C(O)=O)c(C)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.02E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human PPARalpha transfected in human HepG2 cells incubated for 18 hrs by Renilla/Firefly dual-luciferase reporter assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113807 BindingDB Entry DOI: 10.7270/Q2KW5KV0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50574980 (CHEMBL4878808) Show SMILES CCCCOc1ccc2C(=O)\C(Oc2c1)=C\c1cc(C)c(OC(C)(C)C(O)=O)c(C)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	413	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human PPARdelta transfected in human HEK293 cells incubated for 18 hrs by Renilla/Firefly dual-luciferase reporter assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113807 BindingDB Entry DOI: 10.7270/Q2KW5KV0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50574980 (CHEMBL4878808) Show SMILES CCCCOc1ccc2C(=O)\C(Oc2c1)=C\c1cc(C)c(OC(C)(C)C(O)=O)c(C)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	335	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human PPARgamma transfected in human HEK293 cells incubated for 18 hrs by Renilla/Firefly dual-luciferase reporter assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113807 BindingDB Entry DOI: 10.7270/Q2KW5KV0
					More data for this Ligand-Target Pair