Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 475.6 BDBM50437431

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50437431 (CHEMBL2409013) Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NC1CCCc2ncn(C)c12 Show InChI InChI=1S/C25H29N7OS/c1-4-5-10-20-17(24(33)29-19-9-6-8-18-23(19)31(3)15-27-18)14-28-32(20)25-26-13-16(2)22(30-25)21-11-7-12-34-21/h7,11-15,19H,4-6,8-10H2,1-3H3,(H,29,33)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay				ACS Med Chem Lett 4: 790-4 (2013) Article DOI: 10.1021/ml400186z BindingDB Entry DOI: 10.7270/Q24J0GHW
					More data for this Ligand-Target Pair