Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50069364
((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...)Show SMILES CCCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C36H45NO3S/c1-5-6-14-32-26(2)15-18-30(37-32)19-16-27-10-9-12-29(23-27)33(41-25-36(21-22-36)24-34(38)39)20-17-28-11-7-8-13-31(28)35(3,4)40/h7-13,15-16,18-19,23,33,40H,5-6,14,17,20-22,24-25H2,1-4H3,(H,38,39)/b19-16+/t33-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA). |
Bioorg Med Chem Lett 8: 453-8 (1999)
BindingDB Entry DOI: 10.7270/Q2M907SH |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50069364
((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...)Show SMILES CCCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C36H45NO3S/c1-5-6-14-32-26(2)15-18-30(37-32)19-16-27-10-9-12-29(23-27)33(41-25-36(21-22-36)24-34(38)39)20-17-28-11-7-8-13-31(28)35(3,4)40/h7-13,15-16,18-19,23,33,40H,5-6,14,17,20-22,24-25H2,1-4H3,(H,38,39)/b19-16+/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50069364
((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...)Show SMILES CCCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C36H45NO3S/c1-5-6-14-32-26(2)15-18-30(37-32)19-16-27-10-9-12-29(23-27)33(41-25-36(21-22-36)24-34(38)39)20-17-28-11-7-8-13-31(28)35(3,4)40/h7-13,15-16,18-19,23,33,40H,5-6,14,17,20-22,24-25H2,1-4H3,(H,38,39)/b19-16+/t33-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA). |
Bioorg Med Chem Lett 8: 453-8 (1999)
BindingDB Entry DOI: 10.7270/Q2M907SH |
More data for this
Ligand-Target Pair | |