SMILES String Search

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 295.4
BDBM50035324

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor				J Med Chem 37: 3263-73 (1994) BindingDB Entry DOI: 10.7270/Q21R6PJ7
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	304	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor beta expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	391	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D3 expressed in CHO-K1 cells, using [3H]-spiperone as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	419	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]-U-86,170 as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035324 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Displacement of the radioligand [3H]-spiperone from D2 receptor				J Med Chem 37: 3263-73 (1994) BindingDB Entry DOI: 10.7270/Q21R6PJ7
Göteborg University Curated by ChEMBL					More data for this Ligand-Target Pair