Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 326.3 BDBM50425096

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50425096 (CHEMBL2312918) Show SMILES CCCN(c1ccon1)P(=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C18H19N2O2P/c1-2-14-20(18-13-15-22-19-18)23(21,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13,15H,2,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in CHO cells by high throughput planar patch clamp assay				Bioorg Med Chem Lett 23: 706-10 (2013) Article DOI: 10.1016/j.bmcl.2012.11.098 BindingDB Entry DOI: 10.7270/Q2H133BG
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50425096 (CHEMBL2312918) Show SMILES CCCN(c1ccon1)P(=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C18H19N2O2P/c1-2-14-20(18-13-15-22-19-18)23(21,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13,15H,2,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of IK channel (unknown origin)				Bioorg Med Chem Lett 23: 706-10 (2013) Article DOI: 10.1016/j.bmcl.2012.11.098 BindingDB Entry DOI: 10.7270/Q2H133BG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50425096 (CHEMBL2312918) Show SMILES CCCN(c1ccon1)P(=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C18H19N2O2P/c1-2-14-20(18-13-15-22-19-18)23(21,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13,15H,2,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 23: 706-10 (2013) Article DOI: 10.1016/j.bmcl.2012.11.098 BindingDB Entry DOI: 10.7270/Q2H133BG
					More data for this Ligand-Target Pair