Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 503.5 BDBM435302

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM435302 (5-(3-methoxyphenyl)-8-(((trans)-2-(3- methyl-1,2,4...) Show SMILES CCCNC(=O)N1CCc2c(C1)c(CNC(=O)[C@@H]1C[C@H]1c1nc(C)no1)ccc2-c1cccc(OC)c1 |r| Show InChI InChI=1S/C28H33N5O4/c1-4-11-29-28(35)33-12-10-22-21(18-6-5-7-20(13-18)36-3)9-8-19(25(22)16-33)15-30-26(34)23-14-24(23)27-31-17(2)32-37-27/h5-9,13,23-24H,4,10-12,14-16H2,1-3H3,(H,29,35)(H,30,34)/t23-,24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB
					More data for this Ligand-Target Pair