Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM245571
(US9428508, 26)Show SMILES CCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)c12 Show InChI InChI=1S/C27H35N7O4S/c1-4-11-29-39(35,36)23-8-6-5-7-21(23)30-26-24-18(2)17-28-25(24)32-27(33-26)31-20-10-9-19(16-22(20)37-3)34-12-14-38-15-13-34/h5-10,16,18,29H,4,11-15,17H2,1-3H3,(H3,28,30,31,32,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |
Focal adhesion kinase 1
(Homo sapiens (Human)) | BDBM245571
(US9428508, 26)Show SMILES CCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)c12 Show InChI InChI=1S/C27H35N7O4S/c1-4-11-29-39(35,36)23-8-6-5-7-21(23)30-26-24-18(2)17-28-25(24)32-27(33-26)31-20-10-9-19(16-22(20)37-3)34-12-14-38-15-13-34/h5-10,16,18,29H,4,11-15,17H2,1-3H3,(H3,28,30,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |