Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 367.4 BDBM50401709

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50401709 (CHEMBL2205910) Show SMILES CCCNc1ncnc2sc3c(ncn(-c4ccc(OC)cc4)c3=O)c12 Show InChI InChI=1S/C18H17N5O2S/c1-3-8-19-16-13-14-15(26-17(13)21-9-20-16)18(24)23(10-22-14)11-4-6-12(25-2)7-5-11/h4-7,9-10H,3,8H2,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1				Bioorg Med Chem Lett 22: 7223-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.048 BindingDB Entry DOI: 10.7270/Q24B32GJ
					More data for this Ligand-Target Pair