Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 329.8 BDBM50129224

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50129224 (5-Chloro-3-methyl-1H-pyrrole-2,4-dicarboxylic acid...) Show SMILES CCCOC(=O)c1[nH]c(Cl)c(C(=O)OC(C)C(C)(C)C)c1C Show InChI InChI=1S/C16H24ClNO4/c1-7-8-21-15(20)12-9(2)11(13(17)18-12)14(19)22-10(3)16(4,5)6/h10,18H,7-8H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
					More data for this Ligand-Target Pair