Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 394.4 BDBM395377

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395377 (US10308636, Example 109) Show SMILES CCCc1n[nH]c(n1)-c1ccc(cc1)-c1ccc(OCC(C)(C)C(=O)OC)nc1 Show InChI InChI=1S/C22H26N4O3/c1-5-6-18-24-20(26-25-18)16-9-7-15(8-10-16)17-11-12-19(23-13-17)29-14-22(2,3)21(27)28-4/h7-13H,5-6,14H2,1-4H3,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair