Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 510.6 BDBM389791

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389791 (2-Imidazo[4,5-b]pyridin-3-yl-1-{(R)-2-methyl-4-[2-...) Show SMILES CCCc1ncc(cn1)N1CCc2cccc(N3CCN([C@H](C)C3)C(=O)Cn3cnc4cccnc34)c2C1 Show InChI InChI=1S/C29H34N8O/c1-3-6-27-31-15-23(16-32-27)34-12-10-22-7-4-9-26(24(22)18-34)35-13-14-37(21(2)17-35)28(38)19-36-20-33-25-8-5-11-30-29(25)36/h4-5,7-9,11,15-16,20-21H,3,6,10,12-14,17-19H2,1-2H3/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
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