Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50227669
((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)Show SMILES CCN([C@@H]1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H25F3N2O4S/c1-4-28(21(31)27-16-6-8-18(9-7-16)32-23(24,25)26)17-11-14-5-10-19(13-15(14)12-17)33-22(2,3)20(29)30/h5-10,13,17H,4,11-12H2,1-3H3,(H,27,31)(H,29,30)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Johnson& Johnson
Curated by ChEMBL
| Assay Description
Agonist activity at PPARgamma expressed in HEK293 cells by GAL4 transactivation assay |
Bioorg Med Chem Lett 17: 6773-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.041
BindingDB Entry DOI: 10.7270/Q27945H6 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus) | BDBM50227669
((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)Show SMILES CCN([C@@H]1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H25F3N2O4S/c1-4-28(21(31)27-16-6-8-18(9-7-16)32-23(24,25)26)17-11-14-5-10-19(13-15(14)12-17)33-22(2,3)20(29)30/h5-10,13,17H,4,11-12H2,1-3H3,(H,27,31)(H,29,30)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Johnson& Johnson
Curated by ChEMBL
| Assay Description
Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene induction |
Bioorg Med Chem Lett 17: 6773-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.041
BindingDB Entry DOI: 10.7270/Q27945H6 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50227669
((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)Show SMILES CCN([C@@H]1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H25F3N2O4S/c1-4-28(21(31)27-16-6-8-18(9-7-16)32-23(24,25)26)17-11-14-5-10-19(13-15(14)12-17)33-22(2,3)20(29)30/h5-10,13,17H,4,11-12H2,1-3H3,(H,27,31)(H,29,30)/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Johnson& Johnson
Curated by ChEMBL
| Assay Description
Agonist activity at PPARdelta expressed in HEK293 cells by GAL4 transactivation assay |
Bioorg Med Chem Lett 17: 6773-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.041
BindingDB Entry DOI: 10.7270/Q27945H6 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50227669
((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)Show SMILES CCN([C@@H]1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H25F3N2O4S/c1-4-28(21(31)27-16-6-8-18(9-7-16)32-23(24,25)26)17-11-14-5-10-19(13-15(14)12-17)33-22(2,3)20(29)30/h5-10,13,17H,4,11-12H2,1-3H3,(H,27,31)(H,29,30)/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Johnson& Johnson
Curated by ChEMBL
| Assay Description
Agonist activity at PPARalpha expressed in HEK293 cells by GAL4 transactivation assay |
Bioorg Med Chem Lett 17: 6773-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.041
BindingDB Entry DOI: 10.7270/Q27945H6 |
More data for this
Ligand-Target Pair | |