Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50299179
((6aR,9R)-N9,N9-diethyl-N7-(3,4,5-trimethoxyphenyl)...)Show SMILES CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1cc(OC)c(OC)c(OC)c1 |r,c:21| Show InChI InChI=1S/C29H34N4O5/c1-6-32(7-2)28(34)18-11-21-20-9-8-10-22-26(20)17(15-30-22)12-23(21)33(16-18)29(35)31-19-13-24(36-3)27(38-5)25(14-19)37-4/h8-11,13-15,18,23,30H,6-7,12,16H2,1-5H3,(H,31,35)/t18-,23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 564 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assay |
Bioorg Med Chem Lett 19: 6185-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.002
BindingDB Entry DOI: 10.7270/Q2VX0GJN |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50299179
((6aR,9R)-N9,N9-diethyl-N7-(3,4,5-trimethoxyphenyl)...)Show SMILES CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1cc(OC)c(OC)c(OC)c1 |r,c:21| Show InChI InChI=1S/C29H34N4O5/c1-6-32(7-2)28(34)18-11-21-20-9-8-10-22-26(20)17(15-30-22)12-23(21)33(16-18)29(35)31-19-13-24(36-3)27(38-5)25(14-19)37-4/h8-11,13-15,18,23,30H,6-7,12,16H2,1-5H3,(H,31,35)/t18-,23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assay |
Bioorg Med Chem Lett 19: 6185-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.002
BindingDB Entry DOI: 10.7270/Q2VX0GJN |
More data for this
Ligand-Target Pair | |