Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 2
(Homo sapiens (Human)) | BDBM50033095
(CHEMBL3342946)Show SMILES CCN(CC)C(=O)\C=C(/C)c1ccc2oc(C(=O)c3ccc(cc3)C#N)c(NC(=O)C(\C#N)=C(\C)O)c2c1 Show InChI InChI=1S/C29H26N4O5/c1-5-33(6-2)25(35)13-17(3)21-11-12-24-22(14-21)26(32-29(37)23(16-31)18(4)34)28(38-24)27(36)20-9-7-19(15-30)8-10-20/h7-14,34H,5-6H2,1-4H3,(H,32,37)/b17-13+,23-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat... |
ACS Med Chem Lett 5: 1230-4 (2014)
Article DOI: 10.1021/ml500298y
BindingDB Entry DOI: 10.7270/Q2QV3P3H |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50033095
(CHEMBL3342946)Show SMILES CCN(CC)C(=O)\C=C(/C)c1ccc2oc(C(=O)c3ccc(cc3)C#N)c(NC(=O)C(\C#N)=C(\C)O)c2c1 Show InChI InChI=1S/C29H26N4O5/c1-5-33(6-2)25(35)13-17(3)21-11-12-24-22(14-21)26(32-29(37)23(16-31)18(4)34)28(38-24)27(36)20-9-7-19(15-30)8-10-20/h7-14,34H,5-6H2,1-4H3,(H,32,37)/b17-13+,23-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ... |
ACS Med Chem Lett 5: 1230-4 (2014)
Article DOI: 10.1021/ml500298y
BindingDB Entry DOI: 10.7270/Q2QV3P3H |
More data for this
Ligand-Target Pair | |