Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 311.3 BDBM50355222

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50355222 (CHEMBL1835815) Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(F)cc1 Show InChI InChI=1S/C19H18FNO2/c1-3-21(4-2)17-12-18-14(7-10-19(22)23-18)11-16(17)13-5-8-15(20)9-6-13/h5-12H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
					More data for this Ligand-Target Pair