Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296308
(4-(diethylamino)-3-(2-hydroxyethoxy)-N-(5-(3-(trif...)Show SMILES CCN(CC)c1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C24H26F3N3O3S/c1-3-30(4-2)20-9-8-17(14-21(20)33-11-10-31)22(32)29-23-28-15-19(34-23)13-16-6-5-7-18(12-16)24(25,26)27/h5-9,12,14-15,31H,3-4,10-11,13H2,1-2H3,(H,28,29,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296308
(4-(diethylamino)-3-(2-hydroxyethoxy)-N-(5-(3-(trif...)Show SMILES CCN(CC)c1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C24H26F3N3O3S/c1-3-30(4-2)20-9-8-17(14-21(20)33-11-10-31)22(32)29-23-28-15-19(34-23)13-16-6-5-7-18(12-16)24(25,26)27/h5-9,12,14-15,31H,3-4,10-11,13H2,1-2H3,(H,28,29,32) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |