Found 5 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM351535
(N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1- ethylpyrrol...)Show SMILES CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 Show InChI InChI=1S/C25H25Cl2N5O2S/c1-3-32-8-4-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYMPHONY EVOLUTION, INC.
US Patent
| Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo... |
US Patent US9796704 (2017)
BindingDB Entry DOI: 10.7270/Q28K7C6V |
More data for this
Ligand-Target Pair | |
Ephrin type-B receptor 4
(Homo sapiens (Human)) | BDBM351535
(N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1- ethylpyrrol...)Show SMILES CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 Show InChI InChI=1S/C25H25Cl2N5O2S/c1-3-32-8-4-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 525 | n/a | n/a | n/a | n/a | n/a | n/a |
SYMPHONY EVOLUTION, INC.
US Patent
| Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo... |
US Patent US9796704 (2017)
BindingDB Entry DOI: 10.7270/Q28K7C6V |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM351535
(N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1- ethylpyrrol...)Show SMILES CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 Show InChI InChI=1S/C25H25Cl2N5O2S/c1-3-32-8-4-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SYMPHONY EVOLUTION, INC.
US Patent
| Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo... |
US Patent US9796704 (2017)
BindingDB Entry DOI: 10.7270/Q28K7C6V |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 2
(Homo sapiens (Human)) | BDBM351535
(N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1- ethylpyrrol...)Show SMILES CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 Show InChI InChI=1S/C25H25Cl2N5O2S/c1-3-32-8-4-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SYMPHONY EVOLUTION, INC.
US Patent
| Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo... |
US Patent US9796704 (2017)
BindingDB Entry DOI: 10.7270/Q28K7C6V |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM351535
(N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1- ethylpyrrol...)Show SMILES CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 Show InChI InChI=1S/C25H25Cl2N5O2S/c1-3-32-8-4-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SYMPHONY EVOLUTION, INC.
US Patent
| Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo... |
US Patent US9796704 (2017)
BindingDB Entry DOI: 10.7270/Q28K7C6V |
More data for this
Ligand-Target Pair | |