Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 461.5 BDBM50352387

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352387 (CHEMBL1823358) Show SMILES CCNC(=O)C(N1CCN(CC1)c1ccc(NC(=O)C(CC)CC)cc1C#N)c1ccccc1 Show InChI InChI=1S/C27H35N5O2/c1-4-20(5-2)26(33)30-23-12-13-24(22(18-23)19-28)31-14-16-32(17-15-31)25(27(34)29-6-3)21-10-8-7-9-11-21/h7-13,18,20,25H,4-6,14-17H2,1-3H3,(H,29,34)(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
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