Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 454.5 BDBM50352386

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352386 (CHEMBL1823357) Show SMILES CCNC(=O)C(N1CCN(CC1)c1ccc(NC(=O)C(CC)CC)cc1F)c1ccccc1 Show InChI InChI=1S/C26H35FN4O2/c1-4-19(5-2)25(32)29-21-12-13-23(22(27)18-21)30-14-16-31(17-15-30)24(26(33)28-6-3)20-10-8-7-9-11-20/h7-13,18-19,24H,4-6,14-17H2,1-3H3,(H,28,33)(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
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