Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 544.6 BDBM50352385

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352385 (CHEMBL1823356) Show SMILES CCNC(=O)C(N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2cccnc2)cc1C#N)c1ccccc1 Show InChI InChI=1S/C33H32N6O2/c1-2-36-33(41)31(24-9-4-3-5-10-24)39-19-17-38(18-20-39)30-15-14-27(21-26(30)22-34)37-32(40)29-13-7-6-12-28(29)25-11-8-16-35-23-25/h3-16,21,23,31H,2,17-20H2,1H3,(H,36,41)(H,37,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
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