Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 246.2 BDBM50046338

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50046338 (3,3-Difluoro-4-(5-methyl-1H-imidazol-4-yl)-4-oxo-b...) Show SMILES CCOC(=O)CC(F)(F)C(=O)c1[nH]cnc1C Show InChI InChI=1S/C10H12F2N2O3/c1-3-17-7(15)4-10(11,12)9(16)8-6(2)13-5-14-8/h5H,3-4H2,1-2H3,(H,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes				J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3
					More data for this Ligand-Target Pair