Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM167164
(US9073876, 245 | US9732093, Compound 245)Show SMILES CCOC(=O)CCCOc1c(F)c(ccc1C1CCC1)-c1cnc(N)cn1 Show InChI InChI=1S/C20H24FN3O3/c1-2-26-18(25)7-4-10-27-20-14(13-5-3-6-13)8-9-15(19(20)21)16-11-24-17(22)12-23-16/h8-9,11-13H,2-7,10H2,1H3,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 62.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9073876 (2015)
BindingDB Entry DOI: 10.7270/Q28S4NPC |
More data for this
Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM167164
(US9073876, 245 | US9732093, Compound 245)Show SMILES CCOC(=O)CCCOc1c(F)c(ccc1C1CCC1)-c1cnc(N)cn1 Show InChI InChI=1S/C20H24FN3O3/c1-2-26-18(25)7-4-10-27-20-14(13-5-3-6-13)8-9-15(19(20)21)16-11-24-17(22)12-23-16/h8-9,11-13H,2-7,10H2,1H3,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 62.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9732093 (2017)
BindingDB Entry DOI: 10.7270/Q2NV9MCX |
More data for this
Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM167164
(US9073876, 245 | US9732093, Compound 245)Show SMILES CCOC(=O)CCCOc1c(F)c(ccc1C1CCC1)-c1cnc(N)cn1 Show InChI InChI=1S/C20H24FN3O3/c1-2-26-18(25)7-4-10-27-20-14(13-5-3-6-13)8-9-15(19(20)21)16-11-24-17(22)12-23-16/h8-9,11-13H,2-7,10H2,1H3,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 62.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9732093 (2017)
BindingDB Entry DOI: 10.7270/Q2NV9MCX |
More data for this
Ligand-Target Pair | |