Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50013528
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)Show InChI InChI=1S/C22H23NO4/c1-2-25-22(24)11-6-14-26-19-8-5-9-20(15-19)27-16-18-13-12-17-7-3-4-10-21(17)23-18/h3-5,7-10,12-13,15H,2,6,11,14,16H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM) |
J Med Chem 33: 1186-94 (1990)
BindingDB Entry DOI: 10.7270/Q2TB15WM |
More data for this Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50013528
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)Show InChI InChI=1S/C22H23NO4/c1-2-25-22(24)11-6-14-26-19-8-5-9-20(15-19)27-16-18-13-12-17-7-3-4-10-21(17)23-18/h3-5,7-10,12-13,15H,2,6,11,14,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips. |
J Med Chem 33: 1186-94 (1990)
BindingDB Entry DOI: 10.7270/Q2TB15WM |
More data for this Ligand-Target Pair | |