Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 407.4 BDBM50440700

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50440700 (CHEMBL2430984) Show SMILES CCOC(=O)CN[C@@H](Cc1ccccc1)C(=O)Nc1cc(nn1C)-c1ccncc1 |r| Show InChI InChI=1S/C22H25N5O3/c1-3-30-21(28)15-24-19(13-16-7-5-4-6-8-16)22(29)25-20-14-18(26-27(20)2)17-9-11-23-12-10-17/h4-12,14,19,24H,3,13,15H2,1-2H3,(H,25,29)/t19-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...				ACS Med Chem Lett 4: 829-34 (2013) Article DOI: 10.1021/ml4000854 BindingDB Entry DOI: 10.7270/Q2JM2C20
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