Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50098660
((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)Show SMILES CCOC(=O)CNC(=O)c1ccc(cc1)N1CCC(CC1)NC[C@H](O)c1ccc(O)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C25H34N4O7S/c1-3-36-24(32)16-27-25(33)17-4-7-20(8-5-17)29-12-10-19(11-13-29)26-15-23(31)18-6-9-22(30)21(14-18)28-37(2,34)35/h4-9,14,19,23,26,28,30-31H,3,10-13,15-16H2,1-2H3,(H,27,33)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Increased cAMP levels of Chinese hamster ovary (CHO) cells expressing human beta 2 adrenergic receptors |
J Med Chem 44: 1456-66 (2001)
BindingDB Entry DOI: 10.7270/Q2T72J53 |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50098660
((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)Show SMILES CCOC(=O)CNC(=O)c1ccc(cc1)N1CCC(CC1)NC[C@H](O)c1ccc(O)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C25H34N4O7S/c1-3-36-24(32)16-27-25(33)17-4-7-20(8-5-17)29-12-10-19(11-13-29)26-15-23(31)18-6-9-22(30)21(14-18)28-37(2,34)35/h4-9,14,19,23,26,28,30-31H,3,10-13,15-16H2,1-2H3,(H,27,33)/t23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
In vitro increase in cAMP levels in Chinese hamster ovary cells expressing the human cloned beta 3 Adrenergic receptor. |
J Med Chem 44: 1456-66 (2001)
BindingDB Entry DOI: 10.7270/Q2T72J53 |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50098660
((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)Show SMILES CCOC(=O)CNC(=O)c1ccc(cc1)N1CCC(CC1)NC[C@H](O)c1ccc(O)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C25H34N4O7S/c1-3-36-24(32)16-27-25(33)17-4-7-20(8-5-17)29-12-10-19(11-13-29)26-15-23(31)18-6-9-22(30)21(14-18)28-37(2,34)35/h4-9,14,19,23,26,28,30-31H,3,10-13,15-16H2,1-2H3,(H,27,33)/t23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
In vitro activity to increase cAMP levels in Chinese hamster ovary (CHO) cells expressing the cloned human beta 1 Adrenergic receptor |
J Med Chem 44: 1456-66 (2001)
BindingDB Entry DOI: 10.7270/Q2T72J53 |
More data for this
Ligand-Target Pair | |