Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 365.3 BDBM50536165

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50536165 (CHEMBL4550847) Show SMILES CCOC(=O)c1c(C)n(cc(O)c1=O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C21H19NO5/c1-3-26-21(25)19-14(2)22(13-18(23)20(19)24)15-9-11-17(12-10-15)27-16-7-5-4-6-8-16/h4-13,23H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50536165 (CHEMBL4550847) Show SMILES CCOC(=O)c1c(C)n(cc(O)c1=O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C21H19NO5/c1-3-26-21(25)19-14(2)22(13-18(23)20(19)24)15-9-11-17(12-10-15)27-16-7-5-4-6-8-16/h4-13,23H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair