Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 287.3 BDBM50354865

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acrosin (Homo sapiens (Human))	BDBM50354865 (CHEMBL1834546) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1ccc(NC(=O)CC)cc1 Show InChI InChI=1S/C15H17N3O3/c1-3-14(19)16-11-7-5-10(6-8-11)12-9-13(18-17-12)15(20)21-4-2/h5-9H,3-4H2,1-2H3,(H,16,19)(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+7	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of human acrosin using N-alpha-benzoyl-DL-arginine para-nitroanilide-HCl as substrate after 3 hrs by spectrophotometry				Bioorg Med Chem Lett 21: 5822-5 (2011) Article DOI: 10.1016/j.bmcl.2011.07.110 BindingDB Entry DOI: 10.7270/Q2Z32020
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