Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50143707
(2-{4-[2-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-ethyl...)Show SMILES CCOC(=O)c1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C24H33N3O4/c1-2-31-23(30)19-7-3-4-8-20(19)26-14-11-25(12-15-26)13-16-27-21(28)17-24(18-22(27)29)9-5-6-10-24/h3-4,7-8H,2,5-6,9-18H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 4.07 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a.
Curated by ChEMBL
| Assay Description
Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... |
J Med Chem 47: 1900-18 (2004)
Article DOI: 10.1021/jm030944+
BindingDB Entry DOI: 10.7270/Q23F4P35 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50143707
(2-{4-[2-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-ethyl...)Show SMILES CCOC(=O)c1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C24H33N3O4/c1-2-31-23(30)19-7-3-4-8-20(19)26-14-11-25(12-15-26)13-16-27-21(28)17-24(18-22(27)29)9-5-6-10-24/h3-4,7-8H,2,5-6,9-18H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 29.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a.
Curated by ChEMBL
| Assay Description
Binding affinity to the adrenergic receptor alpha-1D of rat aorta |
J Med Chem 47: 1900-18 (2004)
Article DOI: 10.1021/jm030944+
BindingDB Entry DOI: 10.7270/Q23F4P35 |
More data for this
Ligand-Target Pair | |