Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50263652
(3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O |c:15| Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.07E+3 | n/a | n/a | n/a | n/a |
Yuhan Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay |
Bioorg Med Chem Lett 18: 4993-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50263653
((S)-3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin...)Show SMILES CCO[C@@H](Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O |r,c:15| Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28)/t23-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 639 | n/a | n/a | n/a | n/a |
Yuhan Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay |
Bioorg Med Chem Lett 18: 4993-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50263652
(3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O |c:15| Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a |
Yuhan Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay |
Bioorg Med Chem Lett 18: 4993-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50263653
((S)-3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin...)Show SMILES CCO[C@@H](Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O |r,c:15| Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28)/t23-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.73E+3 | n/a | n/a | n/a | n/a |
Yuhan Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay |
Bioorg Med Chem Lett 18: 4993-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G |
More data for this
Ligand-Target Pair | |