Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 637.7 BDBM50211146

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50211146 (2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-[3-(4-et...) Show SMILES CCOCCN([C@H](c1ccccc1)c1nc2ccccc2c(=O)n1-c1ccc(OCC)cc1)C(=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C41H39N3O4/c1-3-47-28-27-43(38(45)29-30-19-21-32(22-20-30)31-13-7-5-8-14-31)39(33-15-9-6-10-16-33)40-42-37-18-12-11-17-36(37)41(46)44(40)34-23-25-35(26-24-34)48-4-2/h5-26,39H,3-4,27-29H2,1-2H3/t39-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
					More data for this Ligand-Target Pair