Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM50514720
(CHEMBL4469237)Show SMILES CCOP(=O)(OCC)C1(Cc2ccccc2)N=CC2C1C(=O)N(C2=O)c1ccccc1 |c:17| Show InChI InChI=1S/C23H25N2O5P/c1-3-29-31(28,30-4-2)23(15-17-11-7-5-8-12-17)20-19(16-24-23)21(26)25(22(20)27)18-13-9-6-10-14-18/h5-14,16,19-20H,3-4,15H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona
Curated by ChEMBL
| Assay Description
Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometry |
J Med Chem 63: 3610-3633 (2020)
Article DOI: 10.1021/acs.jmedchem.9b02080
BindingDB Entry DOI: 10.7270/Q2FB569H |
More data for this
Ligand-Target Pair | |
Nischarin
(Homo sapiens (Human)) | BDBM50514720
(CHEMBL4469237)Show SMILES CCOP(=O)(OCC)C1(Cc2ccccc2)N=CC2C1C(=O)N(C2=O)c1ccccc1 |c:17| Show InChI InChI=1S/C23H25N2O5P/c1-3-29-31(28,30-4-2)23(15-17-11-7-5-8-12-17)20-19(16-24-23)21(26)25(22(20)27)18-13-9-6-10-14-18/h5-14,16,19-20H,3-4,15H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona
Curated by ChEMBL
| Assay Description
Displacement of [3H]clonidine from I1IR in human brain frontal cortex in presence of adrenaline incubated for 45 mins by liquid scintillation spectro... |
J Med Chem 63: 3610-3633 (2020)
Article DOI: 10.1021/acs.jmedchem.9b02080
BindingDB Entry DOI: 10.7270/Q2FB569H |
More data for this
Ligand-Target Pair | |