Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50541958
(CHEMBL4649795)Show SMILES CCOP(=O)(OCC)c1ccc(NC(=O)CCc2ccc(OCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30NO5P/c1-3-31-33(29,32-4-2)25-17-13-23(14-18-25)27-26(28)19-12-21-10-15-24(16-11-21)30-20-22-8-6-5-7-9-22/h5-11,13-18H,3-4,12,19-20H2,1-2H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe-University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-... |
ACS Med Chem Lett 11: 1244-1249 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00102
BindingDB Entry DOI: 10.7270/Q2FB56H6 |
More data for this
Ligand-Target Pair | |
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human)) | BDBM50541958
(CHEMBL4649795)Show SMILES CCOP(=O)(OCC)c1ccc(NC(=O)CCc2ccc(OCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30NO5P/c1-3-31-33(29,32-4-2)25-17-13-23(14-18-25)27-26(28)19-12-21-10-15-24(16-11-21)30-20-22-8-6-5-7-9-22/h5-11,13-18H,3-4,12,19-20H2,1-2H3,(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe-University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna... |
ACS Med Chem Lett 11: 1244-1249 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00102
BindingDB Entry DOI: 10.7270/Q2FB56H6 |
More data for this
Ligand-Target Pair | |