Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitotic checkpoint serine/threonine-protein kinase BUB1
(Homo sapiens (Human)) | BDBM379005
((5R)-5-[({2-[1-(4- ethoxy-2,6- difluorobenzyl)- 1H...)Show SMILES CCOc1cc(F)c(Cn2nc(-c3ncc(OC[C@H]4CCC(=O)N4)c(Nc4ccncc4)n3)c3ccccc23)c(F)c1 |r| Show InChI InChI=1S/C30H27F2N7O3/c1-2-41-20-13-23(31)22(24(32)14-20)16-39-25-6-4-3-5-21(25)28(38-39)30-34-15-26(42-17-19-7-8-27(40)35-19)29(37-30)36-18-9-11-33-12-10-18/h3-6,9-15,19H,2,7-8,16-17H2,1H3,(H,35,40)(H,33,34,36,37)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical
| Assay Description
Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE... |
J Med Chem 51: 4150-69 (2008)
BindingDB Entry DOI: 10.7270/Q2RV0R1M |
More data for this
Ligand-Target Pair | |
Mitotic checkpoint serine/threonine-protein kinase BUB1
(Homo sapiens (Human)) | BDBM379005
((5R)-5-[({2-[1-(4- ethoxy-2,6- difluorobenzyl)- 1H...)Show SMILES CCOc1cc(F)c(Cn2nc(-c3ncc(OC[C@H]4CCC(=O)N4)c(Nc4ccncc4)n3)c3ccccc23)c(F)c1 |r| Show InChI InChI=1S/C30H27F2N7O3/c1-2-41-20-13-23(31)22(24(32)14-20)16-39-25-6-4-3-5-21(25)28(38-39)30-34-15-26(42-17-19-7-8-27(40)35-19)29(37-30)36-18-9-11-33-12-10-18/h3-6,9-15,19H,2,7-8,16-17H2,1H3,(H,35,40)(H,33,34,36,37)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical
| Assay Description
Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE... |
J Med Chem 51: 4150-69 (2008)
BindingDB Entry DOI: 10.7270/Q2RV0R1M |
More data for this
Ligand-Target Pair | |