Found 1 hit in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitotic checkpoint serine/threonine-protein kinase BUB1
(Homo sapiens (Human)) | BDBM341170
(US9765058, Example 2-4-5)Show SMILES CCOc1cc(F)c(Cn2nc(c(F)c2C)-c2ncc(OC)c(Nc3ccncc3C(N)=O)n2)c(F)c1 Show InChI InChI=1S/C24H22F3N7O3/c1-4-37-13-7-16(25)15(17(26)8-13)11-34-12(2)20(27)21(33-34)24-30-10-19(36-3)23(32-24)31-18-5-6-29-9-14(18)22(28)35/h5-10H,4,11H2,1-3H3,(H2,28,35)(H,29,30,31,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft
US Patent
| Assay Description In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ... |
US Patent US9765058 (2017)
BindingDB Entry DOI: 10.7270/Q2JQ1347 |
More data for this Ligand-Target Pair | |