Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM482715
(US10919852, Compound TABLE 1.414 | US11708326, Com...)Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC3(C)C)c2C)c(Cl)cc1CN(C)CCCCC(=O)OC |r| Show InChI InChI=1S/C40H53ClN2O5/c1-7-46-37-26-38(34(41)25-29(37)27-42(5)21-9-8-17-39(44)45-6)48-36-19-18-32-31(14-10-15-33(32)36)30-13-11-16-35(28(30)2)47-24-12-22-43-23-20-40(43,3)4/h10-11,13-16,25-26,36H,7-9,12,17-24,27H2,1-6H3/t36-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22N56DJ |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1
(Homo sapiens) | BDBM482715
(US10919852, Compound TABLE 1.414 | US11708326, Com...)Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC3(C)C)c2C)c(Cl)cc1CN(C)CCCCC(=O)OC |r| Show InChI InChI=1S/C40H53ClN2O5/c1-7-46-37-26-38(34(41)25-29(37)27-42(5)21-9-8-17-39(44)45-6)48-36-19-18-32-31(14-10-15-33(32)36)30-13-11-16-35(28(30)2)47-24-12-22-43-23-20-40(43,3)4/h10-11,13-16,25-26,36H,7-9,12,17-24,27H2,1-6H3/t36-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... |
US Patent US10919852 (2021)
BindingDB Entry DOI: 10.7270/Q2RF5Z3R |
More data for this
Ligand-Target Pair | |