Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM482656
(US10919852, Compound TABLE 1.355 | US11708326, Com...)Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC3(C)C)c2C)c(Cl)cc1CN1CC(C1)C#N |r| Show InChI InChI=1S/C37H44ClN3O3/c1-5-42-35-20-36(32(38)19-27(35)24-40-22-26(21-39)23-40)44-34-14-13-30-29(10-6-11-31(30)34)28-9-7-12-33(25(28)2)43-18-8-16-41-17-15-37(41,3)4/h6-7,9-12,19-20,26,34H,5,8,13-18,22-24H2,1-4H3/t34-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22N56DJ |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1
(Homo sapiens) | BDBM482656
(US10919852, Compound TABLE 1.355 | US11708326, Com...)Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC3(C)C)c2C)c(Cl)cc1CN1CC(C1)C#N |r| Show InChI InChI=1S/C37H44ClN3O3/c1-5-42-35-20-36(32(38)19-27(35)24-40-22-26(21-39)23-40)44-34-14-13-30-29(10-6-11-31(30)34)28-9-7-12-33(25(28)2)43-18-8-16-41-17-15-37(41,3)4/h6-7,9-12,19-20,26,34H,5,8,13-18,22-24H2,1-4H3/t34-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... |
US Patent US10919852 (2021)
BindingDB Entry DOI: 10.7270/Q2RF5Z3R |
More data for this
Ligand-Target Pair | |