Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 572.5 BDBM50310498

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50310498 ((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...) Show SMILES CCOc1ccc(cc1)-n1c(nc2ccccc2c1=O)[C@@H](C)N(Cc1cccnc1)C(=O)Cc1cc(F)c(F)c(F)c1 |r| Show InChI InChI=1S/C32H27F3N4O3/c1-3-42-24-12-10-23(11-13-24)39-31(37-28-9-5-4-8-25(28)32(39)41)20(2)38(19-21-7-6-14-36-18-21)29(40)17-22-15-26(33)30(35)27(34)16-22/h4-16,18,20H,3,17,19H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation counting				Bioorg Med Chem Lett 19: 5114-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.032 BindingDB Entry DOI: 10.7270/Q2FX79KZ
					More data for this Ligand-Target Pair