Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM66574
((5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-v...)Show SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O Show InChI InChI=1S/C25H22N2O8S/c1-3-35-20-10-8-18(9-11-20)26-24(29)23(14-16-7-12-21(28)22(13-16)34-2)36(32,33)25(26)17-5-4-6-19(15-17)27(30)31/h4-15,25,28H,3H2,1-2H3/b23-14+ | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM66574
((5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-v...)Show SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O Show InChI InChI=1S/C25H22N2O8S/c1-3-35-20-10-8-18(9-11-20)26-24(29)23(14-16-7-12-21(28)22(13-16)34-2)36(32,33)25(26)17-5-4-6-19(15-17)27(30)31/h4-15,25,28H,3H2,1-2H3/b23-14+ | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM66574
((5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-v...)Show SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O Show InChI InChI=1S/C25H22N2O8S/c1-3-35-20-10-8-18(9-11-20)26-24(29)23(14-16-7-12-21(28)22(13-16)34-2)36(32,33)25(26)17-5-4-6-19(15-17)27(30)31/h4-15,25,28H,3H2,1-2H3/b23-14+ | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this Ligand-Target Pair | |
Probable nicotinate-nucleotide adenylyltransferase
(Staphylococcus aureus subsp. aureus N315) | BDBM66574
((5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-v...)Show SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O Show InChI InChI=1S/C25H22N2O8S/c1-3-35-20-10-8-18(9-11-20)26-24(29)23(14-16-7-12-21(28)22(13-16)34-2)36(32,33)25(26)17-5-4-6-19(15-17)27(30)31/h4-15,25,28H,3H2,1-2H3/b23-14+ | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 3.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2BV7F7H |
More data for this Ligand-Target Pair | |
Bcl-2-like protein 11
(Homo sapiens (Human)) | BDBM66574
((5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-v...)Show SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O Show InChI InChI=1S/C25H22N2O8S/c1-3-35-20-10-8-18(9-11-20)26-24(29)23(14-16-7-12-21(28)22(13-16)34-2)36(32,33)25(26)17-5-4-6-19(15-17)27(30)31/h4-15,25,28H,3H2,1-2H3/b23-14+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 5.66E+4 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q24J0CKJ |
More data for this Ligand-Target Pair | |
Heat shock factor protein 1
(Mus musculus) | BDBM66574
((5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-v...)Show SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O Show InChI InChI=1S/C25H22N2O8S/c1-3-35-20-10-8-18(9-11-20)26-24(29)23(14-16-7-12-21(28)22(13-16)34-2)36(32,33)25(26)17-5-4-6-19(15-17)27(30)31/h4-15,25,28H,3H2,1-2H3/b23-14+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 8.52E+3 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2P55KXK |
More data for this Ligand-Target Pair | |