Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286296
(5-amino-1-(2,4-dimethylpentan-3- yl)-3-(7-ethoxyqu...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C(C)C)C(C)C)c(N)c1C(N)=O Show InChI InChI=1S/C22H29N5O2/c1-6-29-16-8-7-14-9-15(11-25-17(14)10-16)19-18(22(24)28)21(23)27(26-19)20(12(2)3)13(4)5/h7-13,20H,6,23H2,1-5H3,(H2,24,28) | UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286296
(5-amino-1-(2,4-dimethylpentan-3- yl)-3-(7-ethoxyqu...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C(C)C)C(C)C)c(N)c1C(N)=O Show InChI InChI=1S/C22H29N5O2/c1-6-29-16-8-7-14-9-15(11-25-17(14)10-16)19-18(22(24)28)21(23)27(26-19)20(12(2)3)13(4)5/h7-13,20H,6,23H2,1-5H3,(H2,24,28) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286296
(5-amino-1-(2,4-dimethylpentan-3- yl)-3-(7-ethoxyqu...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C(C)C)C(C)C)c(N)c1C(N)=O Show InChI InChI=1S/C22H29N5O2/c1-6-29-16-8-7-14-9-15(11-25-17(14)10-16)19-18(22(24)28)21(23)27(26-19)20(12(2)3)13(4)5/h7-13,20H,6,23H2,1-5H3,(H2,24,28) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286296
(5-amino-1-(2,4-dimethylpentan-3- yl)-3-(7-ethoxyqu...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C(C)C)C(C)C)c(N)c1C(N)=O Show InChI InChI=1S/C22H29N5O2/c1-6-29-16-8-7-14-9-15(11-25-17(14)10-16)19-18(22(24)28)21(23)27(26-19)20(12(2)3)13(4)5/h7-13,20H,6,23H2,1-5H3,(H2,24,28) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 723 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |