Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286298
(5-amino-3-(7-ethoxyquinolin-3- yl)-1-(3-hydroxybut...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C)C(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C19H23N5O3/c1-4-27-14-6-5-12-7-13(9-22-15(12)8-14)17-16(19(21)26)18(20)24(23-17)10(2)11(3)25/h5-11,25H,4,20H2,1-3H3,(H2,21,26) | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286298
(5-amino-3-(7-ethoxyquinolin-3- yl)-1-(3-hydroxybut...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C)C(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C19H23N5O3/c1-4-27-14-6-5-12-7-13(9-22-15(12)8-14)17-16(19(21)26)18(20)24(23-17)10(2)11(3)25/h5-11,25H,4,20H2,1-3H3,(H2,21,26) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this Ligand-Target Pair | |
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286298
(5-amino-3-(7-ethoxyquinolin-3- yl)-1-(3-hydroxybut...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C)C(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C19H23N5O3/c1-4-27-14-6-5-12-7-13(9-22-15(12)8-14)17-16(19(21)26)18(20)24(23-17)10(2)11(3)25/h5-11,25H,4,20H2,1-3H3,(H2,21,26) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 577 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286298
(5-amino-3-(7-ethoxyquinolin-3- yl)-1-(3-hydroxybut...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C)C(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C19H23N5O3/c1-4-27-14-6-5-12-7-13(9-22-15(12)8-14)17-16(19(21)26)18(20)24(23-17)10(2)11(3)25/h5-11,25H,4,20H2,1-3H3,(H2,21,26) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this Ligand-Target Pair | |