Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286302
(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(CO)CO)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O4/c1-2-27-13-4-3-10-5-11(7-21-14(10)6-13)16-15(18(20)26)17(19)23(22-16)12(8-24)9-25/h3-7,12,24-25H,2,8-9,19H2,1H3,(H2,20,26) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286302
(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(CO)CO)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O4/c1-2-27-13-4-3-10-5-11(7-21-14(10)6-13)16-15(18(20)26)17(19)23(22-16)12(8-24)9-25/h3-7,12,24-25H,2,8-9,19H2,1H3,(H2,20,26) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286302
(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(CO)CO)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O4/c1-2-27-13-4-3-10-5-11(7-21-14(10)6-13)16-15(18(20)26)17(19)23(22-16)12(8-24)9-25/h3-7,12,24-25H,2,8-9,19H2,1H3,(H2,20,26) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286302
(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(CO)CO)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O4/c1-2-27-13-4-3-10-5-11(7-21-14(10)6-13)16-15(18(20)26)17(19)23(22-16)12(8-24)9-25/h3-7,12,24-25H,2,8-9,19H2,1H3,(H2,20,26) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |