Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286295
(5-amino-3-(7-ethoxyquinolin-3- yl)-N,1-bis(2-metho...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(=O)NCCOC Show InChI InChI=1S/C21H27N5O4/c1-4-30-16-6-5-14-11-15(13-24-17(14)12-16)19-18(21(27)23-7-9-28-2)20(22)26(25-19)8-10-29-3/h5-6,11-13H,4,7-10,22H2,1-3H3,(H,23,27) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286295
(5-amino-3-(7-ethoxyquinolin-3- yl)-N,1-bis(2-metho...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(=O)NCCOC Show InChI InChI=1S/C21H27N5O4/c1-4-30-16-6-5-14-11-15(13-24-17(14)12-16)19-18(21(27)23-7-9-28-2)20(22)26(25-19)8-10-29-3/h5-6,11-13H,4,7-10,22H2,1-3H3,(H,23,27) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 321 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this Ligand-Target Pair | |
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286295
(5-amino-3-(7-ethoxyquinolin-3- yl)-N,1-bis(2-metho...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(=O)NCCOC Show InChI InChI=1S/C21H27N5O4/c1-4-30-16-6-5-14-11-15(13-24-17(14)12-16)19-18(21(27)23-7-9-28-2)20(22)26(25-19)8-10-29-3/h5-6,11-13H,4,7-10,22H2,1-3H3,(H,23,27) | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286295
(5-amino-3-(7-ethoxyquinolin-3- yl)-N,1-bis(2-metho...)Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(=O)NCCOC Show InChI InChI=1S/C21H27N5O4/c1-4-30-16-6-5-14-11-15(13-24-17(14)12-16)19-18(21(27)23-7-9-28-2)20(22)26(25-19)8-10-29-3/h5-6,11-13H,4,7-10,22H2,1-3H3,(H,23,27) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 723 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this Ligand-Target Pair | |