Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 355.3 BDBM286294

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uncharacterized protein (Cryptosporidium parvum)	BDBM286294 (5-amino-3-(7-ethoxyquinolin-3- yl)-1-(2-methoxyeth...) Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O3/c1-3-26-13-5-4-11-8-12(10-21-14(11)9-13)16-15(18(20)24)17(19)23(22-16)6-7-25-2/h4-5,8-10H,3,6-7,19H2,1-2H3,(H2,20,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Through its Center For Commercialization US Patent					Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...				US Patent US9518026 (2016) BindingDB Entry DOI: 10.7270/Q2BV7JN4
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM286294 (5-amino-3-(7-ethoxyquinolin-3- yl)-1-(2-methoxyeth...) Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O3/c1-3-26-13-5-4-11-8-12(10-21-14(11)9-13)16-15(18(20)24)17(19)23(22-16)6-7-25-2/h4-5,8-10H,3,6-7,19H2,1-2H3,(H2,20,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Through its Center For Commercialization US Patent					Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...				US Patent US9518026 (2016) BindingDB Entry DOI: 10.7270/Q2BV7JN4
					More data for this Ligand-Target Pair
Calcium-dependent protein kinase 1 (Cryptosporidium parvum)	BDBM286294 (5-amino-3-(7-ethoxyquinolin-3- yl)-1-(2-methoxyeth...) Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O3/c1-3-26-13-5-4-11-8-12(10-21-14(11)9-13)16-15(18(20)24)17(19)23(22-16)6-7-25-2/h4-5,8-10H,3,6-7,19H2,1-2H3,(H2,20,24)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd.					Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...				Bioorg Med Chem Lett 19: 1199-205 (2009) BindingDB Entry DOI: 10.7270/Q23J3G91
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM286294 (5-amino-3-(7-ethoxyquinolin-3- yl)-1-(2-methoxyeth...) Show SMILES CCOc1ccc2cc(cnc2c1)-c1nn(CCOC)c(N)c1C(N)=O Show InChI InChI=1S/C18H21N5O3/c1-3-26-13-5-4-11-8-12(10-21-14(11)9-13)16-15(18(20)24)17(19)23(22-16)6-7-25-2/h4-5,8-10H,3,6-7,19H2,1-2H3,(H2,20,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd.					Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...				Bioorg Med Chem Lett 19: 1199-205 (2009) BindingDB Entry DOI: 10.7270/Q23J3G91
					More data for this Ligand-Target Pair