Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human)) | BDBM323598
(US10188653, Example 6 | US9789110, 6)Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@H]1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C24H30N4O5/c1-2-32-20-10-3-4-11-21(20)33-17-7-6-12-28(15-17)24-25-13-16(14-26-24)22(29)27-19-9-5-8-18(19)23(30)31/h3-4,10-11,13-14,17-19H,2,5-9,12,15H2,1H3,(H,27,29)(H,30,31)/t17-,18-,19+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 222 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o... |
US Patent US9789110 (2017)
BindingDB Entry DOI: 10.7270/Q20G3N81 |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human)) | BDBM323598
(US10188653, Example 6 | US9789110, 6)Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@H]1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C24H30N4O5/c1-2-32-20-10-3-4-11-21(20)33-17-7-6-12-28(15-17)24-25-13-16(14-26-24)22(29)27-19-9-5-8-18(19)23(30)31/h3-4,10-11,13-14,17-19H,2,5-9,12,15H2,1H3,(H,27,29)(H,30,31)/t17-,18-,19+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 222 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o... |
US Patent US10188653 (2019)
BindingDB Entry DOI: 10.7270/Q28G8NS4 |
More data for this
Ligand-Target Pair | |