Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human)) | BDBM323649
((R)-N-(4-amino-2-methyl- 4-oxobutan-2-yl)-2-(3-(2-...)Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC(C)(C)CC(N)=O Show InChI InChI=1S/C23H31N5O4/c1-4-31-18-9-5-6-10-19(18)32-17-8-7-11-28(15-17)22-25-13-16(14-26-22)21(30)27-23(2,3)12-20(24)29/h5-6,9-10,13-14,17H,4,7-8,11-12,15H2,1-3H3,(H2,24,29)(H,27,30)/t17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o... |
US Patent US9789110 (2017)
BindingDB Entry DOI: 10.7270/Q20G3N81 |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human)) | BDBM323649
((R)-N-(4-amino-2-methyl- 4-oxobutan-2-yl)-2-(3-(2-...)Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC(C)(C)CC(N)=O Show InChI InChI=1S/C23H31N5O4/c1-4-31-18-9-5-6-10-19(18)32-17-8-7-11-28(15-17)22-25-13-16(14-26-22)21(30)27-23(2,3)12-20(24)29/h5-6,9-10,13-14,17H,4,7-8,11-12,15H2,1-3H3,(H2,24,29)(H,27,30)/t17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o... |
US Patent US10188653 (2019)
BindingDB Entry DOI: 10.7270/Q28G8NS4 |
More data for this
Ligand-Target Pair | |